International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the  Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing more...


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Original Article


Article page

353-360


Authors Details

Suhasini Padugupati, K. Kiran Kumar, L. Vasantha, D.V.H.S. Sarma


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Study of serum protein and electrophoretic pattern in pumonarytuberculosis patients


Original Article

Author Details : Suhasini Padugupati, K. Kiran Kumar, L. Vasantha, D.V.H.S. Sarma

Volume : 5, Issue : 3, Year : 2018

Article Page : 353-360

https://doi.org/10.18231/2394-6377.2018.0074



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Abstract

Tuberculosis, one of the oldest diseases known to affect humans, particularly in under developed and developing countries and is a major cause of death worldwide. This study deals with the estimation of total serum proteins, albumin levels and its electrophoretic pattern in pulmonary tuberculosis patients and analyses, the changes with reference to the severity of the disease. The present study included a total number of 40 subjects comprising of 20 cases and 20 controls. Total serum protein was estimated by modified biuret end point assay method, albumin by bromocresol green end point assay method and serum protein electrophoresis using Helena electrophoretic apparatus SAS-MX serum protein gel. Total proteins were slightly decreased in cases compared to controls value. Albumin was significantly decreased in cases compared to controls. Alpha-1 globulins slightly increase in cases compared to controls. No change in levels of alpha-2 globulins in controls and cases. Beta globulins very slightly decrease in cases compared to controls. Gamma globulins significantly increases in cases compared to controls. Student’s t-test was performed to test the difference between the groups. The level of significance selected was P-value <0>

Keywords: MTB: Mycobacterium Tuberculosis, Electrophoretic pattern of proteins.


How to cite : Padugupati S, Kumar K K, Vasantha L, Sarma D, Study of serum protein and electrophoretic pattern in pumonarytuberculosis patients. Int J Clin Biochem Res 2018;5(3):353-360

Copyright © 2018 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)