International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the  Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing more...


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Original Article


Article page

17-22


Authors Details

Pragati Khanorkar, B. K. Agrawal, Kiran Kumar B. Sodavadiya


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Role of biochemical markers in type 2 diabetic patients of cataract and retinopathy attending Index Medical College, Hospital and Research Centre, Indore (M.P)


Original Article

Author Details : Pragati Khanorkar, B. K. Agrawal, Kiran Kumar B. Sodavadiya

Volume : 5, Issue : 1, Year : 2018

Article Page : 17-22

https://doi.org/10.18231/2394-6377.2018.0004



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Abstract

Introduction: Aim of the study was to identify the role of selective serum lipids and serum creatinine in the development of type 2 DM microvascular complications like cataract and retinopathy which are potential cause of blindness in these patients.
Materials and Methods: It is a cross sectional study of 100 patients, 50 each of cataract and retinopathy, compared with 50 healthy patients for lipid profile and serum creatinine by Erba 360 automated analyser. The study was carried out from Jan. 2016 to Jun.2017.
Result: In type 2 DM patients there is dyslipidemia i.e. raised levels of serum total cholesterol, triglycerides, low density and very low density lipoproteins and low levels of high density lipoproteins, when compared with the healthy subjects. When compared between cataract and retinopathy patients, serum total cholesterol, low density lipoproteins and LDL/HDL were significantly raised (p < 0.001) in cataract patients whereas serum triglycerides (p< 0.001) and serum creatinine (p< 0.05) levels were significantly raised in retinopathy patients.
Conclusion: cataract and retinopathy are the preventable causes of blindness among the diabetic patients. Timely assessment of lipid profile and serum creatinine may help to detect these complications early and thus prevent the morbidity caused thereby.

Keywords: Cataract, Lipid profile, Retinopathy, Serum creatinine.


How to cite : Khanorkar P, Agrawal B K, Sodavadiya K K B, Role of biochemical markers in type 2 diabetic patients of cataract and retinopathy attending Index Medical College, Hospital and Research Centre, Indore (M.P). Int J Clin Biochem Res 2018;5(1):17-22

Copyright © 2018 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)







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