International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing scientific journals, research content, providing professional’s membership, and conducting conferences, seminars, and award more...

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Original Article


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442- 445


Authors Details

Srinidhi Rai, Tirthal Rai, Swetapadma Nayak, Prajna K


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Serum gamma glutamyl transferase and hs-CRP levels in patients with type 2 diabetes mellitus


Original Article

Author Details : Srinidhi Rai, Tirthal Rai, Swetapadma Nayak, Prajna K

Volume : 3, Issue : 4, Year : 2016

Article Page : 442-445


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Abstract

Introduction: Type 2 diabetes mellitus and its complications is an important health problem.
As oxidative stress and inflammation appears to play a major role in the pathogenesis of diabetes mellitus and development of its complications; we intend to study the serum GGT activity and hs- CRP levels in type 2 diabetes mellitus without complications, type 2diabetes with complications and age and sex matched normal controls.
Materials and Methods: Study consisted of 75 subjects out of whom 25 subjects were type 2 diabetics without any complications, 25 subjects were type 2 diabetics with complications and 25 were age and sex matched normal controls. Serum GGT, serum hsCRP, FBS and glycated hemoglobin were measured in these subjects.
Results: Levels of serum hs- CRP and GGT is increased in type 2 diabetics without any complications and type 2 diabetics with complications, when compared to controls, which was statistically significant (p < 0.001).
Conclusion: Present study showed increase in the levels of hs- CRP and GGT levels in type 2 diabetics without complications and type 2 diabetics with complications when compared to healthy controls. These findings provide evidence that oxidative stress and inflammation plays a role in the pathogenesis of diabetes mellitus and development of its complications.

Keywords: Type 2 diabetes mellitus, Oxidative stress, Inflammation, Gamma glutamyl transferase, High sensitive C- reactive protein


How to cite : Rai S, Rai T, Nayak S, Prajna K, Serum gamma glutamyl transferase and hs-CRP levels in patients with type 2 diabetes mellitus. Int J Clin Biochem Res 2016;3(4):442-445

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