International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing more...
Author Details :
Volume : 3, Issue : 2, Year : 2016
Article Page : 255-258
Background: Type 2 diabetes mellitus (DM) is a disease of impaired carbohydrate metabolism. Vitamin D deiciency and diabetes mellitus are two common conditions and they are widely prevalent across all ages, races, geographical regions, and socioeconomic conditions. The present study aimed to see the effect of 25 hydroxy (OH) vitamin D levels on glycemic control and to show their role in pathogenesis.
Materials and Methods: It was a case control study. The study included 100 cases of clinically diagnosed type 2 DM and 100 age and sex matched healthy controls. Venous blood sample was analysed for fasting blood sugar(FBS), post prandial blood sugar (PPBS), serum 25-OH vitamin D and glycosylated hemoglobin(HbA1c) in both cases and controls. Statistical analysis was done using student’t’ test. Pearson's correlation was performed to establish the relationship between study variables.
Results: There was decreased levels of serum 25-OH vitamin D levels (p<0.001) in cases as compared to the controls. There was negative correlation between 25-OH vitamin D levels and glycosylated hemoglobin (HbA1c) in cases of type 2 DM.
Conclusion: 25-OH Vitamin D levels were lower in patients of type 2 DM as compared to control group. Early detection of vitamin D deficiency and supplementation may help in improvement of glycemic control and prevent complications.
Key words: Type 2 DM, 25 OH Vitamin D, glycosylated hemoglobin
How to cite : Swamy M, Ganiger A, Shankar Prasad Ds, Ratna S, Serum 25- Hydroxy Vitamin D levels in Type 2 Diabetes Mellitus- A Comparative study. Int J Clin Biochem Res 2016;3(2):255-258
Copyright © 2016 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)