International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the  Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing more...


Article type

Original Article


Article page

236-239


Authors Details

D. Sridevi, Amrut A Dambal, Sidrah, Anila Sushma Challa, Samata K. Padaki


View Article As

 


Downlaod Files

   






Article statistics

Viewed: 1380

PDF Downloaded: 683


A Study of Serum Magnesium, Calcium and Phosphorus in Hypothyroidism


Original Article

Author Details : D. Sridevi, Amrut A Dambal, Sidrah, Anila Sushma Challa, Samata K. Padaki

Volume : 3, Issue : 2, Year : 2016

Article Page : 236-239


Suggest article by email


Abstract

Introduction: Hypothyroidism, the commonest form of hormonal dysfunction, is due to thyroid hormone deficiency or its impaired activity. Various electrolyte disturbances in association with hypothyroidism were observed in many studies. The role of thyroid hormones on mineral metabolism is not well understood and the underlying mechanism too. The present study was undertaken to assess and analyze the alterations in the levels of serum calcium, magnesium and phosphorous and their relation with T3, T4 and TSH in hypothyroid state.
Materials and Methods: A case control study was taken up on 40 normal healthy subjects and 40 subjects with thyroid hormone deficiency. Blood sample for analysis was collected from all the subjects. Serum T3, T4, TSH, magnesium, calcium and phosphorous were estimated in all the subjects.
Results: A significant hypocalcemia was observed among cases compared to controls (p<0.0001).Serum phosphorous (p<0.0001) and magnesium(p<0.0001) were significantly increased among cases compared to controls.
Conclusion: The present study indicated significant effect of thyroid hormones on these minerals. This study concludes that serum phosphorous and magnesium levels were high whereas serum calcium level was low in hypothyroidism when compared to normal subjects. A regular follow up of these serum minerals should be done in thyroid hormone deficiency which would be of great help in its management.

Keywords: Calcium, Phosphorous, Magnesium, T3, T4, Thyroid Stimulating Hormone (TSH)


How to cite : Sridevi D, Dambal A A, Sidrah, Challa A S, Padaki S K, A Study of Serum Magnesium, Calcium and Phosphorus in Hypothyroidism. Int J Clin Biochem Res 2016;3(2):236-239

Copyright © 2016 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)