International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the  Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing more...


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Original Article


Article page

226-229


Authors Details

G Rajeswari*, P Satya Gopal, G.B.V.V.S.V Prasad


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Prognostic significance of various biochemical markers in Corona virus disease (COVID)-19: A tertiary care hospital study in Kakinada East Godavari district, Andhra Pradesh


Original Article

Author Details : G Rajeswari*, P Satya Gopal, G.B.V.V.S.V Prasad

Volume : 8, Issue : 3, Year : 2021

Article Page : 226-229

https://doi.org/10.18231/j.ijcbr.2021.047



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Abstract

Background: This study was conducted on covid 19 patients who admitted in various wards in tertiary care centre (Government general hospital, Kakinada) E.G, Dt, Andhra Pradesh, from the 1st November 2020 to 15th January 2021 before Immunization. And divided in to two groups male and female cases. This study involves estimation of Biochemical profile in all the admitted patients to predict the severity of the covid 19 disease at the time of admission in to the Hospital.
Aim and Objectives: To analyse and estimate the serum inflammatory markers like D dimer, Ferritin, C-Reactive Protein, LFT and RFT in Covid 19 patients and evaluate the relationship of inflammatory marker se D-Dimer with other inflammatory markers like Ferritin, CRP and biochemical markers like Creatinine and liver enzymes (OT, PT).
Materials and Methods: We retrospectively analysed the Clinical features and lab parameters of 393 cases of Covid-19 admitted to tertiary care hospital GGH Kakinada.
Results: Plasma d dimer, serum CRP and ferritin were significantly raised in total covid 19 patients and more increased in males when compared with females. Biochemical parameters like creatinine and liver enzymes also elevated in total cases and more increased in males as compared with females suggest organ dysfunction and systemic inflammation. The most typical finding in patients with COVID-19 coagulopathy is an increased D dimer concentration, and the relationship between D-dimer levels and the other markers of inflammation like Ferritin, CRP in COVID-19 shows disease progression.
Conclusion: We conclude that biochemical monitoring of Covid-19 patients helps in identifying critically ill patients even earlier, aiming to reduce mortality and improve the recovery rate.
 

Keywords: Inflammatory markers, Covid-19, Disease progression.


How to cite : Rajeswari G, Gopal P S, Prasad G, Prognostic significance of various biochemical markers in Corona virus disease (COVID)-19: A tertiary care hospital study in Kakinada East Godavari district, Andhra Pradesh. Int J Clin Biochem Res 2021;8(3):226-229

Copyright © 2021 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)







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