International Journal of Clinical Biochemistry and Research

Print ISSN: 2394-6369

Online ISSN: 2394-6377

CODEN : IJCBK6

International Journal of Clinical Biochemistry and Research (IJCBR) open access, peer-reviewed quarterly journal publishing since 2014 and is published under auspices of the  Innovative Education and Scientific Research Foundation (IESRF), aim to uplift researchers, scholars, academicians, and professionals in all academic and scientific disciplines. IESRF is dedicated to the transfer of technology and research by publishing more...


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Review Article


Article page

179-185


Authors Details

Akshaya Sridhar, Monisha Mohan, Kalai Selvi Rajendiran, Priyanka Sekar, Anand Shanker Singh, Selvaraj Nambiar, Ananda Vayaravel Cassinadane*


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Vitamin D nemesis of COVID-19


Review Article

Author Details : Akshaya Sridhar, Monisha Mohan, Kalai Selvi Rajendiran, Priyanka Sekar, Anand Shanker Singh, Selvaraj Nambiar, Ananda Vayaravel Cassinadane*

Volume : 8, Issue : 3, Year : 2021

Article Page : 179-185

https://doi.org/10.18231/j.ijcbr.2021.038



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Abstract

The surge in the spread of the corona virus disease (COVID-19) pandemic alerted us to opt for the preventive medicine, as prevention is always better than cure. Apart from wearing mask, frequent hand washing and social distancing, strengthening our immune response plays a pivotal role in preventing infections. Vitamin D not only aids in calcium and phosphate homeostasis but also acts as an immunomodulator; the deficiency of which is linked with various respiratory and systemic infections. Hence we took up this review to study the effect of vitamin D in corona illness. Vitamin D exerts the expression of pro-inflammatory cytokines, hinders zinc metabolism, lowers Interleukin 6 levels and thereby inhibits cytokine storm in covid patients. Studies have proved that the covid patients have vitamin D deficiency and its supplementation improves the disease severity as well as the length of hospital stay. To conclude, Vitamin D supplementation can protect as well as halt the progression of corona virus disease. Further trials are needed to set the therapeutic levels in various stages of corona illness.
 

Keywords: Vitamin D, Covid- 19, Cytokine storm, Interleukin- 6, Immunomodulation.


How to cite : Sridhar A, Mohan M, Rajendiran K S, Sekar P, Singh A S, Nambiar S, Cassinadane A V, Vitamin D nemesis of COVID-19. Int J Clin Biochem Res 2021;8(3):179-185

Copyright © 2021 by author(s) and Int J Clin Biochem Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)







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