International Journal of Clinical Biochemistry and Research

Official Publication of Innovative Education and Scientific Research Foundation


Current Issue

ISSN (Print): 2394-6369

Online ISSN: 2394-6377

CODEN: IJCBK6

About: International Journal of Clinical Biochemistry and Research (IJCBR) is an open access, peer-reviewed medical quarterly journal, published since 2014 under the auspices of the Innovative Education and Scientific Research Foundation (IESRF), which aims to uplift researchers, scholars, academicians, an more...

Current Issue Highlights
Editorial
The silent partner in the lab – How artificial intelligence is redefining molecular biochemistry
Author details: Sandeep Singh
International Journal of Clinical Biochemistry and Research. 12(3):132-133, 2025.
DOI: 10.18231/j.ijcbr.52086.1761298638
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Review Article
Association of GATA4 polymorphisms with the risk of hypospadias and congenital heart defects in Indian children: A Review
Author details: Divia Paul Aricatt, Neha Samapriya, Somesh M.S.
International Journal of Clinical Biochemistry and Research. 12(3):134-141, 2025.
DOI: 10.18231/j.ijcbr.13060.1759558940
Background: Congenital heart disease (CHD) and hypospadias are common developmental anomalies with both affecting approximately 1% of neonates. Emerging data suggest these conditions often co-occur, hinting at shared genetic pathways. This review evaluates the role of GATA4, a transcription factor i....
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Sickle cell Anemia
Author details: Abhinav Manish
International Journal of Clinical Biochemistry and Research. 12(3):142-148, 2025.
DOI: 10.18231/j.ijcbr.13719.1761022783
Sickle cell disease (SCD) is a monogenic disorder, yet its clinical presentation is influenced by a range of additional genetic and non-genetic factors. Despite decades of study, many aspects of the disease's genetic complexity remain unclear. Affecting millions globally, SCD is among the most commo....
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Original Article
Validation and performance evaluation of biochemical assays in pleural fluid, ascitic fluid, and cerebrospinal fluid: A comprehensive precision, sensitivity, accuracy, and linearity study
Author details: Jayesh Prabhakar Warade, Ashish Anjankar
International Journal of Clinical Biochemistry and Research. 12(3):149-155, 2025.
DOI: 10.18231/j.ijcbr.13447.1759901703
Background: The validation of biochemical assays in pleural fluid, ascitic fluid, and CSF is essential for accurate diagnosis, disease monitoring, and treatment evaluation. This study aims to assess the precision, sensitivity, accuracy, and linearity of biochemical assays performed on these fluids u....
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Aggravated dyslipidemia in comorbid T2DM and hypothyroidism: A Comparative analysis among the peoples of north Bihar
Author details: Zeenat Inam
International Journal of Clinical Biochemistry and Research. 12(3):156-161, 2025.
DOI: 10.18231/j.ijcbr.12165.1852744896
Background: Type 2 diabetes mellitus (T2DM) and hypothyroidism are prevalent endocrine disorders, each associated with significant metabolic disturbances. Their coexistence may exacerbate glycemic and lipid abnormalities, increasing cardiovascular risk. This study aimed to evaluate and compare glyce....
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Serum pentosidine – A surrogate marker of vascular complications in type 2 diabetes mellitus
Author details: Sabiha Naz, Tripti Saxena, Pawan Kumar Kare, Simmi Dube
International Journal of Clinical Biochemistry and Research. 12(3):162-166, 2025.
DOI: 10.18231/j.ijcbr.12870.1971565007
Background: As a result of prolonged hyperglycemia in diabetic patients, glucose reacts with proteins non-enzymatically to produce Advanced Glycation End products (AGES) such as Pentosidine (PEN). These AGEs play a significant role in causing life threatening microvascular (diabetic retinopathy and....
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Anti-inflammatory role of scent leaf (Ocimum Gratissimum L.) and bitter leaf (Vernonia Amygdalina D.) on simulated gastrointestinal digestion
Author details: Umoh Esther Udoa, Oyubu Godspower, Kpomah Bridget, Daramola Festus Olayinkad, Asimi Tawakalitu Temitope, Julius John Dimasf
International Journal of Clinical Biochemistry and Research. 12(3):167-171, 2025.
DOI: 10.18231/j.ijcbr.11445.1760587515
Background: Inflammation can be described as a part of the body’s immune response to any kind of injury or infection. Some of its symptoms include pain, redness, heat and swellings. Inflammation could be acute or chronic depending on the type. Many drugs have been developed to tackle different form....
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Short Communication
Should arterial blood-gas analysis be done in all ICU patients?
Author details: Drishya Pradeep Nair, Asha Khubchandani
International Journal of Clinical Biochemistry and Research. 12(3):172-174, 2025.
DOI: 10.18231/j.ijcbr.13524.1760157016
Introduction: Understanding and use of blood gas analysis enable providers to interpret respiratory, circulatory and metabolic disorders and its severity. It is an important tool of analysis especially amongst critical care patients.Objective: This study was done with the objectiveto find out which....
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